Cutting‑Edge Compounded Options for Scar Management on eNavvi

Scars are not one-size-fits-all. From hypertrophic nodularity to post-inflammatory hyperpigmentation (PIH) and atrophic collagen loss, their presentations—and responses—vary. While over-the-counter silicone gels help some patients, many require targeted formulations to address pigmentation, erythema, and remodeling more precisely.

Compounded scar treatments from eNavvi offer:

• Precision ingredients adjusted to patient phenotype, Fitzpatrick type, and healing stage
• Silicone-plus vehicles (Pracasil® Plus) to enhance absorption while maintaining a moist, occlusive environment
• Streamlined application through single-tube, multitarget formulations that improve adherence

All preparations are fulfilled by Foothills Professional Pharmacy, PCAB-accredited and licensed in all 50 states, with 2-day nationwide shipping and flat transparent pricing: $55 for a 30g, 30-day supply.

Key Compounded Scar Therapies Available on eNavvi

1. Hydroquinone 6% in Pracasil® Plus Base

This high-potency skin-lightening agent remains the gold standard for post-inflammatory hyperpigmentation. Compounded in a silicone-based gel, it provides dual-action benefit: hydroquinone reduces melanin synthesis via tyrosinase inhibition, while Pracasil® Plus softens and flattens scar tissue.

Clinical Use: Best for mature, pigmented scars—especially in Fitzpatrick III–VI skin after acne surgery, trauma, or lasers.

Prescribing Note: Apply a thin layer twice daily for up to 12 weeks; always pair with SPF 50+.

Caution: Contraindicated in pregnancy and breastfeeding. Limit continuous use to under 6 months to reduce risk of ochronosis.

2. Niacinamide 2% + Tretinoin 0.1% in Pracasil® Plus

This multitarget formula combines anti-inflammatory, barrier-restoring, and collagen-remodeling effects, making it ideal for early hypertrophic or mixed-type scars. Niacinamide reduces cytokine activity and transepidermal water loss, while tretinoin upregulates collagenase activity to encourage smoother remodeling.

Clinical Use: Begin 2 weeks post-procedure once epithelialized. Excellent for early surgical, ablative, or traumatic scars.

Prescribing Note: Apply a pea-sized amount nightly for 12–16 weeks. Titrate to every other night for sensitive skin.

Caution: Mild irritation and photosensitivity are expected—ensure patients use broad-spectrum sun protection.

3. Niacinamide 2% in Pracasil® Plus (Mono‑Active)

A minimalist yet effective option for sensitive skin or post-procedural cases unable to tolerate retinoids or hydroquinone. This formulation strengthens the skin barrier, reduces mast-cell-mediated inflammation, and soothes reactivity—making it suitable for both adult and pediatric patients.

Clinical Use: Ideal for postsurgical scars in pregnancy, pediatric dermatology, or rosacea-prone skin.

Prescribing Note: Apply twice daily for a minimum of 8 weeks. Often used as maintenance after more intensive therapies.

Caution: Safe across all skin types and life stages. No known contraindications.

How to Prescribe Scar Compounds via eNavvi

eNavvi’s workflow is designed for clinical speed and patient clarity:

Log in to your eNavvi account and select “Compounded eRx," then "Scar"

Choose your formulation—default SIG, volume, and quantity are preloaded.

E-sign the order and counsel your patient on application schedule and photoprotection.

Track healing via 4-week photographic intervals and adjust formulation or frequency as needed.

Clinical Data Snapshot

• Pracasil® Plus base (silicone + pracaxi oil) achieved >38% improvement on the Vancouver Scar Scale in a 12-week prospective series.
• Hydroquinone 6% improves PIH by 60–70% within 8–12 weeks in skin-of-color studies.
• Tretinoin 0.1% promotes 21% increase in dermal collagen fiber organization after 6 months (histologically confirmed).
• Niacinamide 2% improves barrier strength and reduces inflammation within 6 weeks in split-scar studies.

Key Takeaways for Dermatology Practices

• Compounded scar gels allow personalized, phenotype-specific interventions across scar types and skin tones.
• The Pracasil® Plus base enhances bioavailability while reducing irritation and occlusion-induced maceration.
• All formulas are affordably priced at $55 and ship nationwide within 48 hours—supporting timely care across geographies.
• This model supports high-acuity procedures, enhances adherence, and integrates seamlessly into post-op protocols.